Background:

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

Applications:

ELISA, IHC

Name of antibody:

PSD4

Immunogen:

Fusion protein of human PSD4

Full name:

pleckstrin and Sec7 domain containing 4

Synonyms:

TIC; EFA6B

SwissProt:

Q8NDX1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

30-150