Background:

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, IHC

Name of antibody:

MOG

Immunogen:

Synthetic peptide of human MOG

Full name:

myelin oligodendrocyte glycoprotein

Synonyms:

BTN6; BTNL11; MOGIG2; NRCLP7

SwissProt:

Q16653

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

20-100