Full name:

phosphodiesterase 4D, cAMP-specific

Synonyms:

DPDE3; PDE43; STRK1; ACRDYS2; HSPDE4D; PDE4DN2

Swissprot:

Q08499

Gene Accession:

BC008390

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.